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Updated: Oct 4, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
New headache treatments, including CGRP monoclonal antibodies and neuromodulation, offer options for pregnant and postpartum individuals. Effective headache management is crucial for maternal and infant well-being during prenatal and postnatal care.
Area of Science:
- Neurology
- Obstetrics
- Pharmacology
Background:
- Headache is a prevalent condition affecting pregnant and postpartum individuals.
- Neurologists play a vital role in managing headache disorders in this population.
- Preconception counseling is essential for patients with headache who may become pregnant.
Purpose of the Study:
- To review available headache treatment tools for pregnant and postpartum patients.
- To contextualize new headache therapies for migraine during pregnancy and lactation.
- To emphasize the importance of adequate headache management in prenatal and postnatal care.
Main Methods:
- Review of current literature on headache treatments in pregnancy and lactation.
- Discussion of novel therapies including calcitonin gene-related peptide (CGRP) monoclonal antibodies, lasmiditan, and CGRP antagonists.
- Inclusion of neuromodulation devices as a treatment option.
Main Results:
- Emerging therapies offer expanded options for acute and preventive headache management.
- New treatments like CGRP monoclonal antibodies and lasmiditan are relevant for migraine in pregnancy and lactation.
- Neuromodulation devices present an additional therapeutic avenue.
Conclusions:
- Neurologists must be prepared to manage headache in pregnant patients.
- Identifying secondary headache syndromes during pregnancy and postpartum is critical.
- Collaborative care with obstetric teams is essential for safe and effective treatment of headache during pregnancy and lactation.
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