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Diabetic macular ischemia.

Beatrice Tombolini1,2, Enrico Borrelli1,2, Riccardo Sacconi1,2

  • 1School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

Acta Diabetologica
|February 8, 2022
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography angiography (OCTA) offers a promising alternative for detecting diabetic macular ischemia (DMI). This advanced imaging technique provides detailed insights into DMI, aiding in early diagnosis and prognosis of diabetic retinopathy.

Keywords:
Diabetic macular ischemiaDiabetic retinopathyFluorescein angiographyFoveal avascular zoneOptical coherence tomography angiographyThree-dimensional

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Diabetology

Background:

  • Diabetic retinopathy (DR) poses significant diagnostic and prognostic challenges.
  • Diabetic macular ischemia (DMI) is a key complication impacting visual acuity in DR patients.

Purpose of the Study:

  • To review multimodal imaging approaches for detecting DMI.
  • To evaluate the role of optical coherence tomography angiography (OCTA) in DMI diagnosis and prognosis.

Main Methods:

  • A comprehensive literature search was conducted on PubMed.
  • Keywords included "macular ischemia," "diabetes," and various OCTA and fluorescein angiography (FA) terms.
  • Studies published in English up to October 2021 were reviewed.

Main Results:

  • Optical coherence tomography angiography (OCTA) is emerging as a reliable alternative to fluorescein angiography (FA).
  • OCTA provides qualitative and quantitative assessments of DMI.
  • Three-dimensional (3D) OCTA may identify preclinical changes and predict disease progression.

Conclusions:

  • OCTA has significantly advanced the understanding and detection of DMI.
  • OCTA holds potential for early detection and prognosis of diabetic retinopathy complications.