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Recognition of polymorphic monocyte antigens
Sera from multiparous women and renal transplant recipients were screened for the presence of anti-monocyte antibodies. Reactions caused by anti-HLA antibodies were excluded by using panel cells that were HLA-compatible with the antibody producers. Six sera with monocyte-specific antibodies were identified, and at least two monocyte-specific (probably allelic) antigens could be recognized. The perspective of the clinical significance of typing for monocyte-specific antigens is discussed.
Sera from multiparous women and renal transplant recipients were screened for the presence of anti-monocyte antibodies. Reactions caused by anti-HLA antibodies were excluded by using panel cells that were HLA-compatible with the antibody producers. Six sera with monocyte-specific antibodies were identified, and at least two monocyte-specific (probably allelic) antigens could be recognized. The perspective of the clinical significance of typing for monocyte-specific antigens is discussed.