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Published on: March 22, 2024
[Retracted] Knockdown of PREX2a inhibits the malignant phenotype of osteosarcoma cells
Zixun Dai1, Jie Xie1, Pengfei Lei1
1Department of Orthopedics, Xiangya Hospital of Central South University, Changsha, Hunan 410008, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the Transwell cell migration assay data shown in Fig. 4A and B were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [the original article was published on Molecular Medicine Reports 13: 1930‑1936, 2016; DOI: 10.3892/mmr.2015.4728].
Insights
This study is retracted due to concerns about data duplication in the Transwell cell migration assay. The editors found similarities to previously published or submitted data, leading to the paper's withdrawal.
Area of Science:
- Cell Biology
- Scientific Publishing Ethics
Context:
- Concerns were raised regarding data presented in a published article.
- The data in question involved Transwell cell migration assays.
Purpose:
- To address allegations of data duplication and prior publication.
- To maintain the integrity of scientific records.
Summary:
- The article published in Molecular Medicine Reports has been retracted.
- Retraction is due to the discovery of strikingly similar data to other publications, indicating potential data duplication and violation of prior publication policies.
- Authors failed to provide a satisfactory explanation for the data discrepancies.
Impact:
- Upholds scientific integrity by removing compromised research.
- Informs the scientific community about the retraction and its reasons.
- Reinforces the importance of ethical data presentation in scientific publications.
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