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Pseudomyxoma Peritonei - A Case Report
Ruhee Tuladhar1, Eliza Shrestha1, Rishikesh Narayan Shrestha2
1Department of Gynecological Oncology, Bhaktapur Cancer Hospital, Bhaktapur, Nepal.
Journal of Nepal Health Research Council
|February 10, 2022
Summary
A 53-year-old woman with post-menopausal bleeding and abdominal pain was diagnosed with bilateral ovarian and colon mucinous carcinoma with omental metastasis. This case highlights a rare presentation of pseudomyxoma peritonei originating from multiple adenocarcinomas.
Area of Science:
- Gynecologic Oncology
- Gastrointestinal Oncology
- Pathology
Background:
- Pseudomyxoma peritonei (PMP) is a rare condition characterized by mucinous ascites, typically arising from appendiceal or ovarian tumors.
- Ovarian and colorectal adenocarcinomas are common primary sources, but PMP can present insidiously.
Observation:
- A 53-year-old female presented with a 3-month history of abdominal pain and 2 days of post-menopausal bleeding.
- Computed tomography (CT) revealed bilateral adnexal masses and ascites, with elevated cancer antigen 19-9 (CA19.9) and carcinoembryonic antigen (CEA) levels.
Findings:
- Histopathological examination of resected tissues confirmed mucinous carcinoma involving bilateral ovaries and the colon, with omental metastasis.
- The findings suggest a diagnosis of pseudomyxoma peritonei secondary to synchronous or metastatic adenocarcinomas of ovarian and colonic origin.
Implications:
- This case underscores the importance of considering multiple primary sites in the differential diagnosis of PMP, especially with concurrent ovarian and gastrointestinal findings.
- Multidisciplinary management is crucial for optimizing outcomes in patients with PMP arising from complex metastatic patterns.
