[Research advances in contact lens-associated dry eye]

Area of Science:

• Ophthalmology
• Ocular Surface Disease

Background:

• Dry eye disease is a prevalent ophthalmic condition affecting patient quality of life and public health.
• Contact lens wear is a recognized risk factor, leading to a higher incidence of dry eye in wearers.
• Contact lens-associated dry eye (CLADE) was classified as iatrogenic dry eye in 2017, highlighting its clinical significance.

Purpose of the Study:

• To review the latest research on contact lens-associated dry eye (CLADE).
• To cover the epidemiology, pathogenesis, diagnosis, prevention, and treatment of CLADE.
• To increase awareness and understanding of CLADE among ophthalmologists.

Main Methods:

• Literature review of recent studies on CLADE.
• Synthesis of information on CLADE's risk factors, mechanisms, and clinical aspects.

Main Results:

• CLADE is increasingly recognized as an important complication of contact lens wear.
• Ophthalmologists have historically focused more on severe complications like keratitis, potentially undervaluing CLADE.
• Current research provides insights into the multifactorial nature and management strategies for CLADE.

Conclusions:

• CLADE is a significant public health issue linked to contact lens use.
• Further research and clinical attention are needed to better understand and manage CLADE.
• Improved awareness and diagnostic/treatment approaches for CLADE are crucial for contact lens wearers.