Non-ischemic Painful Intermittent Left Bundle Branch Block With Infra-Hisian Block Treated Successfully With
Rana Al-Zakhari1, Safa Aljammali1, Nicholas Sheets1
1Internal Medicine, Richmond University Medical Center, New York, USA.
Insights
Non-ischemic painful left bundle branch block (LBBB) causes chest pain due to ventricular dyssynchrony. Treatment with a biventricular pacemaker successfully resolved symptoms in a patient with intermittent LBBB.
Area of Science:
- Cardiology
- Electrophysiology
- Clinical Case Reports
Background:
- Non-ischemic painful left bundle branch block (LBBB) is a rare condition characterized by chest pain coinciding with LBBB appearance and resolution.
- The exact mechanism remains unclear, though ventricular dyssynchrony is a proposed cause.
Observation:
- A 65-year-old male presented with non-ischemic chest pain and intermittent left bundle branch block (ILBBB) with infra-Hisian conduction delay.
- Coronary artery disease was ruled out via angiography.
- An electrophysiology study was performed to investigate the cause of chest pain and guide management.
Findings:
- The patient's ILBBB and associated chest pain were successfully managed with a biventricular pacemaker.
- Electrophysiology studies are crucial for diagnosing painful LBBB in the absence of coronary artery disease.
Implications:
- This case underscores the diagnostic value of electrophysiology studies in unexplained painful LBBB.
- Biventricular pacing may be an effective treatment for symptomatic LBBB related to ventricular dyssynchrony.
- Further research into the pathophysiology of non-ischemic painful LBBB is warranted.
Abstract:
Non-ischemic painful left bundle branch block (LBBB) is defined as chest pain that occurs simultaneously with the appearance of left bundle branch block and resolves with the disappearance of the left bundle branch block in patients without evidence of myocardial ischemia. The underlying mechanism of this rare clinical occurrence has not been fully understood, but it has been proposed that it results from ventricular dyssynchrony. In this case report, we present a 65-year-old male with non-ischemic chest pain who was found to have intermittent left bundle branch block (ILBBB) with infra-Hisian conduction delay, treated successfully with a biventricular pacemaker. After excluding the presence of angiographic coronary artery disease, an electrophysiology study was conducted to direct the management and investigate other causes of chest pain. The present study highlights the importance of obtaining electrophysiology studies in patients with painful left bundle branch block with no angiographic evidence of coronary artery disease to diagnose this uncommon syndrome.
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