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Published on: September 20, 2018
First reported case of Cladosporium para-aortic abscess
Racha Ibrahim1, Zeina Bou Chebel1, Rindala Saliba2
1Hotel-Dieu de France, St Joseph University, Infectious Disease Department, Beirut, Lebanon.
Abstract:
Cladosporium species are ubiquitous dematiaceous fungi, widely found in the indoor and outdoor environments. They are considered a frequent source of contamination in laboratory settings. In human pathology, Cladosporium is a main agent of phaeohyphomycosis, known to cause subcutaneous and brain abscess, especially in immunocompromised hosts. The route of disseminated infections is mainly hematogenous after inhalation of the spores. However, a direct inoculation could be possible. We report the first case of a para-aortic abscess with thrombus formation, caused by Cladosporium spp., after a valvular replacement surgery, in an immunocompetent patient. This raises the alarm about the rapid identification of the source of contamination in the operating room, in order to prevent the emergence of further fatal infections.
Insights
Cladosporium fungi can cause serious infections, even in healthy individuals, following surgery. Prompt identification of contamination sources in operating rooms is crucial to prevent fatal outcomes.
Area of Science:
- Mycology
- Infectious Diseases
- Surgical Pathology
Background:
- Cladosporium species are common fungi found indoors and outdoors.
- They are known causes of phaeohyphomycosis, particularly in immunocompromised individuals.
- Infections typically occur via spore inhalation, leading to abscesses.
Observation:
- A rare case of para-aortic abscess with thrombus formation is presented.
- The abscess was caused by Cladosporium species.
- The patient was immunocompetent and had undergone valvular replacement surgery.
Findings:
- This is the first reported case of Cladosporium-induced para-aortic abscess post-cardiac surgery.
- Direct inoculation during surgery is a potential route of infection.
- The source of contamination in the operating room was suspected.
Implications:
- Highlights the risk of Cladosporium infections in immunocompetent patients after surgery.
- Emphasizes the need for rapid identification of intraoperative contamination sources.
- Underscores the potential for fatal infections if contamination is not controlled.
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