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Primary orbital pleomorphic liposarcoma in a child: A case report
Trakanta Wannapanich1, Paitoon Pratipanawat1
1Faculty of Medicine, Khon Kaen University, Thailand.
American Journal of Ophthalmology Case Reports
|February 11, 2022
Summary
This case report details a rare pediatric orbital pleomorphic liposarcoma in an 11-year-old boy. Total orbital exenteration proved effective for local control in the absence of metastasis.
Area of Science:
- Oncology
- Ophthalmology
- Pathology
Background:
- Pleomorphic liposarcoma is an exceptionally rare tumor, particularly in pediatric orbital locations.
- Orbital masses require careful diagnostic evaluation to differentiate benign from malignant entities.
Observation:
- An 11-year-old boy presented with a rapidly enlarging, painless lower eyelid mass.
- Imaging demonstrated a large, well-circumscribed orbital mass.
- Histopathological analysis confirmed pleomorphic liposarcoma, a rare spindle cell neoplasm.
Findings:
- Despite chemotherapy, the orbital tumor showed resistance and continued growth.
- Total orbital exenteration was performed for local disease control.
- The patient remained disease-free at 6-month follow-up, indicating successful surgical management.
Implications:
- This case highlights the diagnostic and therapeutic challenges of pediatric orbital pleomorphic liposarcoma.
- Histopathology is crucial for definitive diagnosis.
- Surgical resection, such as total orbital exenteration, is the preferred treatment for localized disease without metastasis.
