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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
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Cancer Cell Migration through Invadopodia01:35

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Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However,...
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Updated: Oct 4, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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[Appendiceal cancer].

M R Kayumov1, N A Kiryanov1, R R Musaev1

  • 1Izhevsk State Medical Academy, Izhevsk, Russia.

Khirurgiia
|February 11, 2022
PubMed
Summary
This summary is machine-generated.

Appendiceal cancer, a rare tumor, is often diagnosed late. This case highlights diagnostic challenges and the need for advanced methods for timely appendiceal cancer treatment.

Keywords:
appendiceal cancerappendicular infiltratediagnostic laparotomy

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Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Appendiceal cancer is an exceptionally rare malignancy.
  • Diagnosis frequently occurs incidentally during appendectomy or post-mortem.
  • Late diagnosis often results from the disease's subtle and variable presentation.

Purpose of the Study:

  • To report a case of appendiceal cancer diagnosed during the management of appendicular infiltrate.
  • To review the existing literature on appendiceal cancer diagnosis and management.
  • To emphasize the diagnostic difficulties associated with appendiceal cancer.

Main Methods:

  • Case report of appendiceal cancer identified during treatment for appendicular infiltrate.
  • Comprehensive literature review on appendiceal cancer.

Main Results:

  • The presented case underscores the diagnostic challenges of appendiceal cancer.
  • Appendiceal cancer's variable clinical course complicates differential diagnosis.
  • Delayed diagnosis can impede prompt and effective treatment initiation.

Conclusions:

  • Accurate and timely diagnosis of appendiceal cancer is crucial for patient outcomes.
  • Clinical expertise alone is insufficient; novel diagnostic technologies are essential.
  • New diagnostic tools are needed to improve accuracy and reduce diagnostic errors in appendiceal cancer.