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Selenium and vitamins A, E, and C: nutrients with cancer prevention properties
Journal of the American Dietetic Association
|April 1, 1986
Summary
Dietary nutrients like selenium and vitamins A, C, and E show potential as anticarcinogens. While more research is needed, increasing dietary intake may help prevent some cancers and support conventional therapies.
Area of Science:
- Nutritional Science
- Oncology
- Cancer Prevention
Background:
- Diet is linked to an estimated 35% of cancer incidence.
- Specific nutrients may play a role in reducing cancer risk.
- Vitamins and minerals possess anticarcinogenic properties.
Purpose of the Study:
- To explore the role of selenium and vitamins A, C, and E in cancer prevention.
- To review evidence on nutrient-carcinogen interactions.
- To discuss the potential of nutrients as adjuncts to cancer therapy.
Main Methods:
- Review of epidemiological and animal data.
- Analysis of nutrient actions and interactions relevant to cancer.
- Evaluation of existing human trials on nutrient efficacy.
Main Results:
- Epidemiological and animal studies suggest nutrients act as anticarcinogens.
- These nutrients may alter cancer incidence, differentiation, and growth.
- Limited human trials exist, but data indicate potential benefits.
Conclusions:
- Nutrients like selenium and vitamins A, C, and E may help prevent certain cancers.
- Dietary intake is preferred over supplements due to potential unidentified beneficial food components.
- Further research is necessary before widespread recommendations for nutrient supplementation.