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Updated: Oct 4, 2025
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Cultivation Methods of Spirochetes from Borrelia burgdorferi Sensu Lato Complex and Relapsing Fever Borrelia
Published on: November 25, 2022
5.8K
[Borreliosis and relapsing fever]
Alice Raffetin1, Solène Patrat-Delon2, Céline Cazorla3
1Centre de Référence des maladies vectorielles à tiques (CRMVT), Paris et région Nord, CH Villeneuve-Saint- Georges, France.
La Revue Du Praticien
|February 11, 2022
Summary
Relapsing fevers borreliosis (RFB) are bacterial infections transmitted by lice or ticks. Early diagnosis via microscopy or PCR and prompt treatment with doxycycline or ceftriaxone are crucial for a good outcome.
Area of Science:
- Infectious Diseases
- Bacteriology
- Epidemiology
Background:
- Relapsing fevers borreliosis (RFB) are caused by Borrelia bacteria, transmitted by arthropods like lice and ticks.
- Louse-borne RFB occurs epidemically during crises, while tick-borne RFB is geographically distributed and sporadic.
Purpose of the Study:
- To summarize the transmission, clinical presentation, diagnosis, treatment, and outcomes of relapsing fevers borreliosis.
Main Methods:
- Review of transmission vectors (lice, ticks) and geographical distribution.
- Description of clinical manifestations, including incubation period and recurrent fever patterns.
- Overview of diagnostic methods (microscopy, PCR, culture) and treatment protocols (doxycycline, ceftriaxone).
Main Results:
- Incubation period ranges from 3 to 20 days, with recurrent fevers averaging every 7 days.
- Diagnosis is aided by abundant bacteremia during febrile phases.
- Mortality rates vary from 2-5%, with generally good outcomes after treatment.
Conclusions:
- RFB is a treatable condition with a generally favorable prognosis when diagnosed and managed promptly.
- Understanding transmission dynamics and clinical features is key for effective public health interventions.
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