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Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Updated: Oct 3, 2025

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Published on: September 27, 2021

Ocular Nanomedicine.

Zhimin Tang¹, Xianqun Fan¹, Yu Chen²

¹Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, 200011, P. R. China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|February 12, 2022

Summary

This summary is machine-generated.

Conventional eye treatments face limitations. Nanomedicine offers advanced diagnostics and therapeutics, improving drug delivery and enabling new biomimetic approaches for ocular applications.

Keywords:

diagnostics nanomedicine ocular ophthalmology therapeutics

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Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Area of Science:

Ophthalmology
Nanomedicine
Material Science

Background:

Conventional therapeutic strategies in clinical ophthalmology have intrinsic shortcomings that compromise treatment efficacy.
Advances in material science, nanochemistry, and nanobiotechnology have driven the development of functional nanosystems for ophthalmologic applications.

Purpose of the Study:

To comprehensively review recent progress in nanosystems, including conventional and emerging nanomaterials, for ophthalmology.
To emphasize the role of physicochemical properties of nanomaterials in ocular bioavailability, tissue penetration, biodistribution, and elimination.
To explore emerging theranostic methodologies and biomimetic approaches for multipurpose ocular applications.

Main Methods:

Review of state-of-the-art studies on nanosystems in ophthalmology.
Analysis of the fundamental physicochemical properties of nanomaterials.
Examination of surface engineering of nanomaterials for advanced applications.

Main Results:

Nanosystems offer versatile alternatives to conventional treatments, addressing limitations in efficacy.
Physicochemical properties of nanomaterials significantly influence their behavior within the ocular microenvironment.
Emerging theranostic methodologies and biomimetic systems show potential for enhanced ocular applications.

Conclusions:

Ocular nanomedicine presents a promising field for improving ophthalmic diagnostics and therapeutics.
Further research into challenges and future directions is crucial for clinical translation of ocular nanomedicine.
Biomimetic ophthalmology and theranostic nanosystems represent key areas for future development.