Recent Advances in Organoselenium Catalysis.
Santosh G1, Samata E Shetgaonkar1, Fateh V Singh1
1Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology Chennai, Chennai-600127, Tamil Nadu, India.
Current Organic Synthesis
|February 14, 2022
Summary
Organoselenium chemistry offers versatile reagents for organic synthesis and catalysis. This review highlights recent advancements in organoselenium catalysis, including asymmetric applications.
Area of Science:
- Synthetic Chemistry
- Medicinal Chemistry
- Organocatalysis
Background:
- Organoselenium chemistry is a key area in synthetic and medicinal chemistry.
- Organoselenium reagents facilitate diverse organic transformations like selenocyclizations and selenoxide eliminations.
Purpose of the Study:
- To review recent progress in organoselenium reagents used in catalysis.
- To highlight the development and application of asymmetric organoselenium variants.
Main Methods:
- Review of literature on organoselenium catalysis.
- Discussion of stoichiometric and catalytic applications of organoselenium reagents.
- Examination of various organic and inorganic oxidants for catalytic species regeneration.
Main Results:
- Organoselenium reagents are effective as both stoichiometric reagents and organocatalysts.
- Successful application in various synthetic transformations.
- Development of asymmetric organoselenium catalysts.
Conclusions:
- Organoselenium chemistry provides powerful catalytic tools for organic synthesis.
- Asymmetric organoselenium catalysis is an expanding field with significant potential.
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