Related Experiment Video

Updated: Jul 22, 2026

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

Role of the toxicology laboratory in suspected ingestions

B Hepler, C Sutheimer, I Sunshine

    Pediatric Clinics of North America
    |April 1, 1986
    PubMed

    Keywords:
    Toxicology labIngestion diagnosisClinical laboratory practicesHospital diagnostics

    More Related Videos

    Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones06:06

    Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

    Published on: February 5, 2018

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    Related Concept Videos

    Toxic Reactions: Overview01:26

    Toxic Reactions: Overview

    When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
    Toxicity falls into two primary categories: local and systemic.
    Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
    In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
    Prevention of Further Absorption of Poison01:14

    Prevention of Further Absorption of Poison

    In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
    Enhanced Elimination of Poison01:26

    Enhanced Elimination of Poison

    Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
    Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
    Renal excretion is the...
    Toxicity Testing in Animals01:23

    Toxicity Testing in Animals

    Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
    Pharmaceutical Poisoning: Potential Scenarios01:26

    Pharmaceutical Poisoning: Potential Scenarios

    Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
    Pharmaceutical Poisoning: Treatment Strategies01:26

    Pharmaceutical Poisoning: Treatment Strategies

    Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...