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Updated: Oct 3, 2025

Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration

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Published on: January 22, 2014

Genetically engineered materials: Proteins and beyond.

Jingjing Wei¹, Lianjie Xu², Wen-Hao Wu²

¹College of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, 455000 China.

Science China. Chemistry

|February 14, 2022

Summary

This summary is machine-generated.

Genetically engineered materials (GEMs) leverage genetic sequences for tunable properties, offering advantages over traditional materials. This review explores protein-based and living materials, highlighting potential for synthetic material exploration.

Keywords:

genetic engineering living materials protein self-assembly

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Area of Science:

Materials Science
Biotechnology
Synthetic Biology

Background:

Genetically engineered materials (GEMs) offer tunable properties encoded within genetic sequences.
Nature utilizes information-rich molecules, particularly proteins, for material construction.
Living materials integrate biological components with nonbiological factors for advanced functionalities.

Purpose of the Study:

To elaborate on the concept and applications of genetically engineered materials (GEMs).
To review progress in engineered protein materials and engineered living materials.
To discuss the potential for nonbiological and synthetic GEMs.

Main Methods:

Review of current literature on protein engineering and living materials.
Analysis of examples showcasing the capabilities of GEMs.
Exploration of the theoretical framework for synthetic GEMs.

Main Results:

Engineered protein materials allow for sequence-based property optimization.
Living materials demonstrate synergistic functions through biological and nonbiological component integration.
Existing GEMs predominantly use biological building blocks, leaving synthetic avenues underexplored.

Conclusions:

GEMs represent a powerful paradigm for creating advanced materials with precisely controlled properties.
Protein engineering is key to developing high-performance biomaterials.
Expanding GEM development to synthetic and nonbiological systems holds significant future potential.