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Self-reported medication adherence and pharmacy refill adherence among persons with ischemic stroke: a
Helena Norberg1, Maria Sjölander2, Eva-Lotta Glader3
1Department of Integrative Medical Biology, Umeå University, S-901 87, Umea, Sweden. helena.norberg@umu.se.
European Journal of Clinical Pharmacology
|February 14, 2022
Summary
Medication adherence in stroke patients differs between self-reports (MARS-5) and pharmacy refills (SPDR). Different patient factors predict adherence, indicating these methods capture distinct aspects of medication taking.
Area of Science:
- Neurology
- Pharmacology
- Public Health
Background:
- Ischemic stroke survivors require long-term medication management.
- Assessing medication adherence is crucial for treatment effectiveness.
- Discrepancies exist between self-reported and pharmacy refill adherence measures.
Purpose of the Study:
- To compare self-reported adherence (MARS-5) with pharmacy refill data (SPDR) in ischemic stroke patients.
- To identify predictors of adherence for each assessment method.
Main Methods:
- A cohort of ischemic stroke patients was surveyed using the MARS-5.
- Pharmacy refill data from the SPDR were used to assess adherence over two years.
- Multivariable logistic regression analyzed adherence and its predictors.
Main Results:
- 87% reported adherence via MARS-5, while 78% showed adherence via SPDR.
- Only 70% were adherent by both measures.
- Predictors differed: female sex for MARS-5, male sex and younger age for SPDR.
Conclusions:
- Most ischemic stroke patients were adherent by at least one measure.
- Discrepancies between MARS-5 and SPDR suggest they capture different adherence facets.
- Understanding these differences is key for accurate adherence assessment in stroke care.
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