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Aptamer-based Emerging Tools for Viral Biomarker Detection: A Focus on SARS-CoV-2
Prabir Kumar Kulabhusan1, Parsa Pishva2, Eda Çapkın2
1Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, Belfast, UK.
Current Medicinal Chemistry
|February 14, 2022
Summary
Rapid aptamer-based biosensors offer a promising solution for early viral detection. These advanced tools provide sensitive, specific, and cost-effective diagnostics for infectious diseases like COVID-19.
Area of Science:
- Biotechnology
- Molecular Diagnostics
- Biosensor Technology
Background:
- Viral infections pose significant threats to human and animal health, necessitating rapid and accurate diagnostic tools.
- The COVID-19 pandemic highlighted the urgent need for advanced viral detection platforms that are fast, affordable, and highly sensitive.
- Current viral detection methods face challenges in sensitivity and quantification, driving the search for superior alternatives.
Conclusions:
- Aptamers are highly promising as synthetic binding molecules for developing next-generation viral diagnostic tools.
- Aptamer-based biosensors can overcome limitations of current methods, offering improved sensitivity and quantification.
- These platforms have the potential to revolutionize high-throughput viral detection and other biomedical applications.
