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Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

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In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
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Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

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Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
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Pharmacovigilance01:19

Pharmacovigilance

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
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Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

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Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
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Enhanced Elimination of Poison01:26

Enhanced Elimination of Poison

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Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
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Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

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Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
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Related Experiment Video

Updated: Oct 3, 2025

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
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2020 webPOISONCONTROL data summary.

Nicole E Reid1, Kelly Johnson-Arbor2, Susan Smolinske3

  • 1National Capital Poison Center, Washington, DC, United States of America; The George Washington University School of Medicine, Washington, DC, United States of America.

The American Journal of Emergency Medicine
|February 14, 2022
PubMed
Summary
This summary is machine-generated.

webPOISONCONTROL, an online tool, managed over 156,000 poison exposure cases in 2020, offering a digital alternative to phone-based poison centers. It demonstrated potential for real-time public health surveillance, including detecting COVID-19-related exposure trends.

Keywords:
Internet-based interventionOnline access to poison controlPoison control centersPoisoning epidemiologyPopulation surveillance

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Area of Science:

  • Toxicology and Public Health Surveillance

Background:

  • Increasing internet use for health information has reduced reliance on traditional telephone-based poison centers in the U.S.
  • webPOISONCONTROL was developed as a browser-based tool and app to provide online, personalized recommendations for human poison exposures.

Purpose of the Study:

  • To characterize cases managed by webPOISONCONTROL in 2020.
  • To evaluate the tool's potential for real-time monitoring of poisoning incidents.
  • To compare webPOISONCONTROL case demographics and exposure types with traditional poison center data.

Main Methods:

  • Analysis of 156,202 completed, nonduplicated public cases entered into webPOISONCONTROL during 2020.
  • Data were analyzed using a custom Qlik Sense dashboard for case characterization and trend identification.

Main Results:

  • webPOISONCONTROL managed 156,202 cases, with 52.9% involving children under 4 years old.
  • Pharmaceuticals accounted for 41.5% of cases, while nonpharmaceuticals comprised 58.5%. Common categories included cosmetics and cleaning substances.
  • The platform identified near real-time increases in exposures to hand sanitizers and cleaners during the COVID-19 pandemic, showcasing surveillance capabilities.

Conclusions:

  • webPOISONCONTROL serves as a safe, quick, and automated alternative for individuals unable or unwilling to contact traditional poison centers via phone.
  • The platform effectively handles a significant volume of poison exposure cases, particularly among young children, and provides valuable public health surveillance data.