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Related Concept Videos

Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

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Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
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Biological Methods for Microbial Control01:28

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Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

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Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
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The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
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Metallic Structures: Effective Agents to Fight Pathogenic Microorganisms.

Diana Pereira1, Tiago Soares Carreira2, Nuno Alves2

  • 1CICS-UBI-Health Sciences Research Centre, Universidade da Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal.

International Journal of Molecular Sciences
|February 15, 2022
PubMed
Summary
This summary is machine-generated.

Metals show promise as antimicrobial agents against pathogens like viruses, bacteria, and fungi. This review explores their mechanisms and applications in combating infectious diseases, including coronavirus disease 2019 (COVID-19).

Keywords:
antimicrobial agentsbacteriafungimetalsvirus

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Area of Science:

  • Microbiology
  • Materials Science
  • Infectious Diseases

Background:

  • The coronavirus disease 2019 (COVID-19) pandemic highlighted the significant threat posed by microorganisms to global health.
  • Historical outbreaks demonstrate the recurring risk of microbial pathogens to human survival.
  • Developing effective antimicrobial strategies is crucial for public health and pandemic preparedness.

Purpose of the Study:

  • To provide a comprehensive overview of the current state-of-the-art in using metals as antimicrobial agents.
  • To elucidate the mechanisms by which metals combat various pathogens.
  • To review the application of metals in fighting viruses, bacteria, and fungi.

Main Methods:

  • Literature review of recent studies on metal-based antimicrobial applications.
  • Analysis of scientific data on the efficacy of different metals against diverse pathogens.
  • Examination of proposed mechanisms of antimicrobial action for various metal formats.

Main Results:

  • Metals, in various forms, are extensively studied for their antimicrobial properties.
  • Different metals exhibit distinct mechanisms for inhibiting or killing pathogens.
  • Evidence supports the use of metals against a range of microbial threats, including viruses, bacteria, and fungi.

Conclusions:

  • Metals represent a significant class of antimicrobial solutions with broad-spectrum efficacy.
  • Understanding metal-pathogen interactions is key to developing novel antimicrobial therapies.
  • Continued research into metal-based antimicrobials is vital for future infectious disease control.