Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The aging lung.

D A Mahler, R A Rosiello, J Loke

    Clinics in Geriatric Medicine
    |May 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Aging naturally reduces lung function, decreasing elasticity and muscle strength. This impacts breathing capacity and gas exchange, making it crucial to differentiate normal aging from disease.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    FLT3 inhibitors in acute myeloid leukaemia: assessment of clinical effectiveness, adverse events and future research-a systematic review and meta-analysis.

    Systematic reviews·2020
    Same author

    Impact of patient: donor HLA disparity on reduced-intensity-conditioned allogeneic stem cell transplants from HLA mismatched unrelated donors for AML: from the ALWP of the EBMT.

    Bone marrow transplantation·2020
    Same author

    Biallelic mutations in FLNB cause a skeletal dysplasia with 46,XY gonadal dysgenesis by activating β-catenin.

    Clinical genetics·2017
    Same author

    The Physiology of Marathon Running.

    The Physician and sportsmedicine·2016
    Same author

    Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia.

    Annals of hematology·2014
    Same author

    Spectroscopic detection of exogenous materials in latent fingerprints treated with powders and lifted off with adhesive tapes.

    Analytical and bioanalytical chemistry·2014
    Same journal

    Cardiovascular Prevention in Older Adults: From Estimation to Treatment.

    Clinics in geriatric medicine·2026
    Same journal

    Preventive Cardiology for the Clinically Complex Older Adult.

    Clinics in geriatric medicine·2026
    Same journal

    A Preventive Neurology Perspective on Promoting Brain Health and Preventing Cardiovascular Disease.

    Clinics in geriatric medicine·2026
    Same journal

    Secondary Prevention in Older Adults: Putting It All Together.

    Clinics in geriatric medicine·2026
    Same journal

    Primary Prevention in Older Adults: Putting It All Together.

    Clinics in geriatric medicine·2026
    Same journal

    Managing Bleeding Risk in Older Adults: Antithrombotics and Anticoagulants.

    Clinics in geriatric medicine·2026
    See all related articles

    Area of Science:

    • Pulmonary physiology
    • Geriatric respiratory medicine

    Background:

    • The respiratory system undergoes significant structural and functional changes with age.
    • Decreased lung elasticity, increased chest wall stiffness, and reduced respiratory muscle strength are characteristic of aging.
    • These age-related changes can affect various respiratory parameters.

    Purpose of the Study:

    • To elucidate the structural and functional alterations in the aging respiratory system.
    • To highlight the impact of aging on lung mechanics, gas exchange, and respiratory control.
    • To emphasize the importance of distinguishing normal aging from pathological conditions.

    Main Methods:

    • Review of physiological changes associated with aging in the respiratory system.
    • Analysis of factors influencing age-related respiratory decline, including smoking.

    Related Experiment Videos

  • Synthesis of current understanding of lung aging.
  • Main Results:

    • Advancing age leads to decreased lung elasticity and respiratory muscle strength.
    • Forced vital capacity, expiratory flow rates, and diffusing capacity progressively decline with age.
    • Cigarette smoking exacerbates the age-related decline in expiratory flow rates.

    Conclusions:

    • Aging is associated with predictable declines in respiratory function.
    • Understanding these normal aging changes is essential for accurate diagnosis of respiratory diseases in older adults.
    • Differentiating aging effects from pathology is critical for appropriate patient management.