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A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos

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Published on: November 8, 2014

Zebrafish information network, the knowledgebase for Danio rerio research.

Yvonne M Bradford¹, Ceri E Van Slyke¹, Leyla Ruzicka¹

¹The Institute of Neuroscience, University of Oregon, Eugene, OR 97403-1254, USA.

|February 15, 2022

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The Zebrafish Information Network (ZFIN) provides comprehensive Danio rerio genetic and genomic data, integrating resources for understanding human biology and disease. ZFIN

Area of Science:

Genomics and Bioinformatics
Model Organism Research
Comparative Genomics

Background:

The Zebrafish Information Network (ZFIN) has been a central repository for Danio rerio genetic and genomic data since 1994.
ZFIN expertly curates, integrates, and displays diverse zebrafish research data, including genes, alleles, phenotypes, and gene function.
Data accessibility is enhanced through nomenclature, curatorial activities, web interfaces, and data downloads, adhering to FAIR principles.

Purpose of the Study:

To provide an overview of the data resources available at the Zebrafish Information Network (ZFIN).
To highlight recent updates and new features enhancing data accessibility and integration.
To describe ZFIN's role within the Alliance of Genome Resources for understanding human biology and disease.

Main Methods:

Keywords:

Danio rerio database knowledgebase zebrafish

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Last Updated: Oct 3, 2025

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos

A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos

Published on: November 8, 2014

Regular Care and Maintenance of a Zebrafish Danio rerio Laboratory: An Introduction

Regular Care and Maintenance of a Zebrafish Danio rerio Laboratory: An Introduction

Published on: November 18, 2012

Construction of an Affordable and Easy-to-Build Zebrafish Facility

Construction of an Affordable and Easy-to-Build Zebrafish Facility

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Data curation and integration of zebrafish genetic and genomic information.
Development of web interfaces and data download options for user accessibility.
Collaboration with other model organism databases to form the Alliance of Genome Resources.

Main Results:

Recent updates to the ZFIN gene page include access to single-cell RNA sequencing data.
Integration with the Alliance of Genome Resources provides links to Alliance web pages and enhanced data interoperability.
Ribbon diagrams are now available to summarize biological systems and Gene Ontology annotations.

Conclusions:

The Zebrafish Information Network (ZFIN) continues to be a vital resource for Danio rerio research.
Recent updates and integration with the Alliance of Genome Resources significantly enhance data utility for studying human biology and disease.
ZFIN's commitment to data curation and accessibility supports the broader goals of model organism-based research.