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Updated: Oct 3, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Dengue induced reversible blindness.

Anju Dinkar¹, Jitendra Singh², Virendra Atam³

¹Department of Microbiology, Institute of Medical Science, BHU, Varanasi, UP, India.

Journal of Vector Borne Diseases

|February 16, 2022

Summary

This summary is machine-generated.

Dengue fever, transmitted by Aedes aegypti mosquitoes, can cause severe complications like retinal hemorrhage and pancytopenia. This case report highlights a young student

Keywords:

Anaemia Ophthalmic complication Pancytopenia Retinal haemorrhage Thrombocytopenia

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Area of Science:

Infectious Diseases
Virology
Ophthalmology

Background:

Dengue fever is a mosquito-borne viral illness.
Typically self-limiting, it can present with severe, atypical manifestations.
The clinical spectrum of dengue is continually evolving.

Observation:

A young male student presented with dengue fever.
Complications included retinal hemorrhage and severe pancytopenia.
The patient experienced unusual dengue manifestations.

Findings:

The patient's dengue infection led to significant hematological and ocular complications.
Severe pancytopenia and retinal hemorrhage were key clinical features.
The case demonstrates the expanding clinical profile of dengue.

Implications:

This case underscores the importance of recognizing unusual dengue presentations.
Early diagnosis and management are crucial for severe dengue cases.
Further research into expanding dengue manifestations is warranted.