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Related Experiment Videos

Fetal lateral ventricular ratio determination during the second trimester.

D H Pretorius, J A Drose, M L Manco-Johnson

    Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
    |March 1, 1986
    PubMed
    Summary
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    The lateral ventricular ratio (LVR) helps diagnose fetal ventriculomegaly. This study validates normal LVR ranges in the second trimester, aiding accurate ultrasound diagnosis of abnormal ventricular size.

    Area of Science:

    • Medical Imaging
    • Fetal Medicine
    • Neurology

    Background:

    • Ventriculomegaly diagnosis relies on identifying abnormal ventricular size via ultrasound.
    • The lateral ventricular ratio (LVR) is a key index for differentiating normal from enlarged ventricles.
    • Accurate LVR ranges are crucial, especially before 24 weeks gestation when diagnosis can be challenging.

    Purpose of the Study:

    • To validate previously reported data on the normal range of the lateral ventricular ratio (LVR) during the second trimester of pregnancy.
    • To establish reliable sonographic reference values for fetal ventricular size.
    • To improve the diagnostic accuracy of ventriculomegaly in early fetal development.

    Main Methods:

    • Calculation of LVRs from 122 normal fetal ultrasound examinations.

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  • Measurements were taken by three independent observers.
  • Data collected weekly from 15 to 25 weeks of gestation.
  • Main Results:

    • Lateral ventricular ratios (LVR) ranged from 56 +/- 18% at 15 weeks to 33 +/- 4% at 25 weeks.
    • Normal lateral ventricular width (LVW) was 0.7-1.1 cm.
    • Hydrocephalic fetuses showed LVW ranging from 1.1-2.7 cm.

    Conclusions:

    • The LVR is highly effective in distinguishing ventriculomegaly from normal ventricular size.
    • Serial ultrasound examinations in the second trimester are often necessary for definitive diagnosis.
    • A lateral ventricular width (LVW) under 1.1 cm typically indicates normal ventricular size.