Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple dose insulin regimen using the NovoPen: initial experience and approximate dose requirements.

P J Dunn, D R Jury

    The New Zealand Medical Journal
    |April 9, 1986
    PubMed
    Summary

    This study shows that a new multidose insulin pen improved blood glucose control in poorly controlled diabetic patients. The NovoPen was reliable and convenient, with reduced hypoglycemia frequency observed.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Methodological approaches in 16S sequencing of female reproductive tract in fertility patients: a review.

    Journal of assisted reproduction and genetics·2024
    Same author

    Investigation of Mitochondrial Related Variants in a Cerebral Small Vessel Disease Cohort.

    Molecular neurobiology·2022
    Same author

    Investigating diagnostic sequencing techniques for CADASIL diagnosis.

    Human genomics·2020
    Same author

    Genetic variants associated with exercise performance in both moderately trained and highly trained individuals.

    Molecular genetics and genomics : MGG·2020
    Same author

    Ligneous conjunctivitis and the cervix.

    BJOG : an international journal of obstetrics and gynaecology·2003
    Same author

    A novel route to substituted 4-methylene-4,5-dihydroisoxazoles mediated by hafnium(IV) chloride.

    Chemical communications (Cambridge, England)·2002

    Area of Science:

    • Endocrinology
    • Diabetes Management

    Background:

    • Insulin therapy is crucial for managing diabetes mellitus.
    • Conventional insulin injection regimens may present challenges in achieving optimal glycemic control.
    • New delivery devices aim to improve patient convenience and treatment efficacy.

    Purpose of the Study:

    • To evaluate the initial experience with a novel multidose insulin pen (NovoPen) for multiple daily insulin injections.
    • To assess the impact of this new regimen on glycemic control and hypoglycemia frequency in insulin-dependent diabetic patients.

    Main Methods:

    • A cohort of 14 insulin-dependent diabetic patients was studied.
    • Patients were transitioned from conventional twice-daily insulin injections to a multiple-dose regimen using the NovoPen.
    • Glycemic control was assessed using HbA1% values, and hypoglycemia frequency was monitored.

    Related Experiment Videos

    Main Results:

    • Total daily insulin dosage remained consistent between the conventional and multidose regimens.
    • Significant improvement in glycemic control (HbA1%) was observed in patients with initially poor control.
    • No significant change in glycemic control was noted in patients with initially excellent control.
    • Hypoglycemia frequency appeared reduced with the multiple-dose regimen, particularly in some patients with excellent baseline control.
    • The NovoPen was found to be reliable, convenient, and well-accepted by most patients.

    Conclusions:

    • The multidose NovoPen insulin injector offers a viable option for improving glycemic control in poorly controlled diabetic patients.
    • This new insulin delivery system demonstrates potential for reducing hypoglycemia and enhancing patient convenience.
    • Further research is warranted to confirm these initial findings in larger cohorts.