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Intraoperative flow cytometry for invasive breast cancer conserving surgery: A new alternative or adjunct to cavity

Georgios S Markopoulos1, Haralambos Harissis2, Maria Andreou3

  • 1Haematology Laboratory-Unit of Molecular Biology, University Hospital of Ioannina, Ioannina, Greece; Neurosurgical Institute, University of Ioannina School of Medicine, Ioannina, Greece.

Surgical Oncology
|February 18, 2022
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Breast conserving surgeryIntraoperative diagnosisIntraoperative flow cytometry

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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