Iron-Catalyzed Oxidative C-O and C-N Coupling Reactions Using Air as Sole Oxidant

We describe the oxygenation of tertiary arylamines, and the amination of tertiary arylamines and phenols. The key step of these coupling reactions is an iron-catalyzed oxidative C-O or C-N bond formation which generally provides the corresponding products in high yields and with excellent regioselectivity. The transformations are accomplished using hexadecafluorophthalocyanine-iron(II) (FePcF₁₆ ) as catalyst in the presence of an acid or a base additive and require only ambient air as sole oxidant.