Related Concept Videos
02:02Genomics
37.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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01:11Genome-wide Association Studies-GWAS
14.5K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
14.5K
02:46Genetic Screens
5.1K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.1K
01:20Applications of Molecular Taxonomy
166
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
166
02:34DNA Microarrays
18.8K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
18.8K
03:36Genome Annotation and Assembly
19.5K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Related Experiment Video
Updated: Oct 3, 2025
09:37
An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
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Integrated Genome Browser App Store.
Sameer Shanbhag1, Riddhi Patil1, Noor Zahara1
1Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Bioinformatics (Oxford, England)
|February 18, 2022
Summary
A new App Store for the Integrated Genome Browser (IGB) centralizes sharing of visualization tools. This platform connects developers and researchers, accelerating genome data exploration and understanding.
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Area of Science:
- Genomics
- Bioinformatics
- Software Development
Background:
- Genome science is advancing rapidly, necessitating faster development of visualization software.
- The Integrated Genome Browser (IGB) was re-factored into a pluggable framework (IGB Apps) to facilitate new visualization development.
Purpose of the Study:
- To address the lack of a centralized repository for sharing IGB Apps.
- To create a user-friendly platform connecting IGB App developers with potential users.
Main Methods:
- Development of a dedicated website to serve as an App Store for IGB Apps.
- Implementation of features for developers to release and document their Apps.
- Creation of a searchable interface for users to discover and find relevant Apps.
Main Results:
- A user-friendly App Store for IGB has been successfully created and launched.
- The platform provides a centralized location for sharing and discovering IGB Apps.
- Facilitates easier connection between IGB App developers and researchers.
Conclusions:
- The IGB App Store enhances the discoverability and accessibility of genome visualization tools.
- This initiative supports the rapid advancement of genome science by streamlining software development and sharing.
- Encourages collaboration and innovation within the IGB user community.