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Updated: Oct 3, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
SEBORRHEIC KERATOSIS: CURRENT STATE OF THE PROBLEM
Mykhailo S Myroshnychenko1, Tetiana M Moiseienko2, Inna I Torianyk2
1KHARKIV NATIONAL MEDICAL UNIVERSITY, KHARKIV, UKRAINE.
Seborrheic keratosis is increasingly affecting younger individuals (31-50 years old) and is more prevalent in men. This study highlights the importance of morphological diagnosis due to discrepancies with clinical findings.
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Seborrheic keratosis (SK) is a common benign skin tumor.
- Understanding its epidemiological and morphological characteristics is crucial for accurate diagnosis and management.
Purpose of the Study:
- To identify the age, gender, clinical, and morphological features of seborrheic keratosis.
- To highlight the "rejuvenation" trend and diagnostic discrepancies.
Main Methods:
- Analysis of biopsy materials from 196 patients clinically diagnosed with SK.
- Evaluation of patient age, gender, and lesion localization.
- Pathohistological examination using hematoxylin and eosin staining and microscopy.
Main Results:
- SK shows a "rejuvenation" trend, predominantly affecting patients aged 31-50.
- More common in men, typically on the face, scalp, neck, and back.
- High discrepancy between clinical and morphological diagnoses; hyperkeratotic and acanthotic variants are most common. A rare case of malignant transformation into squamous cell carcinoma was noted.
Conclusions:
- The study identified key age, gender, and morphological features of SK.
- Findings aid in better understanding and diagnosing this condition across medical specialties.
- Emphasizes the need for improved clinical methods and highlights the critical role of morphological analysis.
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