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Updated: Oct 3, 2025

Establishing a Device for Sleep Deprivation in Mice
Published on: September 22, 2023
The effect of one-night sleep deprivation on cognitive functions in healthy young adults
Serkan Pekçetin1, Gülnur Öztürk2, Buse Çetin3
1University of Health Sciences Turkey, Faculty of Gülhane Health Sciences, Department of Occupational Therapy- Ankara, Turkey.
Introduction:
The effects of acute sleep deprivation on cognitive function have not been clearly elucidated. The purpose of this study was to evaluate changes in cognitive function in healthy adults after one night of sleep deprivation.
Material And Methods:
Twenty-one healthy young adults (aged 18-30 years) underwent assessment of cognitive functions before and after one night of total sleep deprivation and an age- and gender-matched control group was assessed before and after a normal night sleep. Cognitive functions were assessed using the Montreal cognitive assessment (MOCA) and trail making test (TMT) parts A and B.
Results:
General linear model repeated measures demonstrated an insignificant effect for time × group (sleep deprivation) interaction for MOCA, TMT Part A, and TMT Part B scores after one-night sleep deprivation (p>.05 for all).
Conclusion:
A single night of sleep deprivation, which can be inevitable in modern society, had no significant effect on cognitive performance in healthy adults.
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