Jove
Visualize
Contact Us

Related Concept Videos

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model01:13

Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model

132
Drugs administered through various routes can lead to nonlinear elimination, resulting in complex pharmacokinetic behaviors crucial to understanding efficacious drug dosing.
When a drug is administered through a constant intravenous infusion and eliminated via nonlinear pharmacokinetics, it follows zero-order input. For example, oral drugs undergo first-order absorption upon administration and are eliminated through nonlinear pharmacokinetics.
In the case of subcutaneously administered drugs,...
132
Optimizing Chromatographic Separations01:15

Optimizing Chromatographic Separations

529
Optimizing chromatographic separations is crucial for obtaining clean separations in a minimum amount of time. Optimization is required for several factors, including kinetic effects related to band broadening, plate height, capacity factor, and separation factor.
Band broadening refers to spreading solute bands as they travel through the column. This broadening can impact resolution. Plate height (H) represents the length required for one theoretical plate. A lower plate height corresponds to...
529

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-layer network biology combined with single-cell evidence reveals core regulatory nodes in atherosclerotic plaques and potential drug-targeting directions.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

A Study on Traceable Oxygen-Releasing Microspheres in Combination with Bone Marrow Mesenchymal Stem Cells to Enhance Skin Wound Healing.

International journal of molecular sciences·2026
Same author

A Flexible Wireless Passive Platform for Decoupled Electrolyte and Temperature Sensing Toward Heat‑Stress Assessment.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Self-Powered Flexible Hydrogel Sensor with Unbreakable Compressible Tolerance for Multiple Tactile Perception.

Nano letters·2026
Same author

Latent transforming growth factor binding protein-2 (LTBP2), an IPF biomarker of clinical decline, promotes TGF-beta signaling and lung fibrosis in mice.

American journal of respiratory cell and molecular biology·2026
Same author

Machine learning-driven alignment architecture of heterogeneous data with transient varying semantics.

Nature communications·2026
Same journal

Impact of an Artificial Albumin Corona on Surface Charge-Driven Nano-Bio Interactions and Cytotoxicity of Silver Nanoparticles.

ACS omega·2026
Same journal

Structural and Functional Disruption of Thiopurine S‑Methyltransferase by the A80P Variant: A Simulation and Genotyping Study.

ACS omega·2026
Same journal

CRISPR/Cas12a2-Mediated Ultrasensitive Assay for Rapid Detection of H1N1 Influenza Virus RNA.

ACS omega·2026
Same journal

Photocatalytic Treatment of Real Sugar Industry Wastewater Using Lignocellulosic Biomass-Derived Hydrochar/g-CN.

ACS omega·2026
Same journal

Electrochemical Dopamine Biosensor Based on Plant-Derived Peroxidase Immobilized on Titanate Nanowires.

ACS omega·2026
Same journal

Revealing the Effects of Process Parameters on Structural, Thermal, Mechanical, Biodegradation, and Biocompatibility Properties on the Electrospinning of Poly(vinyl alcohol)/Microbial Inulin Nanofibers.

ACS omega·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Oct 3, 2025

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner
06:34

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner

Published on: October 25, 2017

8.0K

Optimizing Bleaching Operating Conditions Based on Mathematical Programming to Reduce AOX Emissions.

Yongjun Yin1,2, Shaoxu Chen1,2, Zhichao Ma3

  • 1College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China.

ACS Omega
|February 21, 2022
PubMed
Summary
This summary is machine-generated.

This study optimized eucalyptus elemental chlorine-free (ECF) bleaching to reduce adsorbable organic halogen (AOX) emissions. By modeling and adjusting operating conditions, AOX was reduced by 12.5%, demonstrating an effective strategy for cleaner pulp production.

More Related Videos

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations
14:33

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations

Published on: October 1, 2013

14.5K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.4K

Related Experiment Videos

Last Updated: Oct 3, 2025

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner
06:34

Operation of a 25 KWth Calcium Looping Pilot-plant with High Oxygen Concentrations in the Calciner

Published on: October 25, 2017

8.0K
Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations
14:33

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations

Published on: October 1, 2013

14.5K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.4K

Area of Science:

  • Environmental Chemistry
  • Chemical Engineering
  • Pulp and Paper Industry

Background:

  • Elemental Chlorine-Free (ECF) bleaching is a key process in pulp production.
  • Adsorbable Organic Halogen (AOX) compounds in wastewater are significant environmental pollutants.
  • Optimizing ECF bleaching is crucial for reducing AOX emissions and improving sustainability.

Purpose of the Study:

  • To optimize an ECF bleach plant for eucalyptus pulp to minimize adsorbable organic halogen (AOX) emissions.
  • To establish calculation models for pulp quality and AOX content based on operating conditions.
  • To develop and validate an optimization model for AOX reduction.

Main Methods:

  • Analysis of correlations between operating conditions (e.g., chlorine dioxide dosage) and pulp quality/AOX.
  • Development of calculation models for pulp quality indices and wastewater AOX content.
  • Structuring an optimization model focused on minimizing AOX emission, validated by experimental data.

Main Results:

  • Calculation models demonstrated good simulation accuracy (within 6.3% error).
  • Reduced chlorine dioxide in the D0 stage was identified as the most impactful factor for AOX reduction.
  • Optimization successfully reduced AOX emissions from 90.84 kg/h to 79.58 kg/h (a 12.5% decrease).

Conclusions:

  • The developed optimization model effectively reduces AOX emissions in eucalyptus ECF bleaching.
  • Adjusting operating conditions, particularly chlorine dioxide in the D0 stage, significantly impacts AOX levels.
  • The study provides a validated, data-driven approach for environmentally sustainable pulp bleaching.