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Updated: Oct 2, 2025
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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
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Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging: From Basic Concepts to Emerging Methods.
Robert J Holtackers1,2,3, Tilman Emrich4,5,6, René M Botnar3,7
1Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands.
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|February 23, 2022
Summary
Late gadolinium enhancement (LGE) cardiac MRI is the standard for assessing myocardial viability. Ongoing advancements in imaging techniques continue to enhance its diagnostic capabilities for various cardiomyopathies.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Medical Diagnostics
Background:
- Late gadolinium enhancement (LGE) is a cornerstone cardiac magnetic resonance imaging (MRI) technique.
- It has been validated against histology for over two decades.
- Its clinical utility and applications in diagnosing cardiomyopathies have significantly expanded.
Purpose of the Study:
- To review the fundamental concepts of LGE imaging.
- To discuss its diagnostic and prognostic value.
- To explore recent advancements and future directions in LGE MRI.
Main Methods:
- Review of basic concepts in LGE imaging.
- Elaboration on diagnostic and prognostic applications.
- Discussion of recent developments and emerging techniques in cardiac MRI.
Main Results:
- Continuous improvements in 3D imaging, motion correction, and water/fat-separated techniques enhance LGE performance.
- Scar quantification methods further refine the utility of LGE imaging.
- These developments have expanded the clinical applications of LGE MRI.
Conclusions:
- LGE imaging remains the noninvasive reference standard for myocardial viability assessment.
- Enhanced spatial resolution and scar-to-blood contrast solidify its role.
- Ongoing technological progress continually improves LGE MRI's performance and clinical utility.
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