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Updated: Oct 2, 2025

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Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method
Published on: October 27, 2020
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The Effects of Space Radiation and Microgravity on Ocular Structures
Bahadır Özelbaykal1, Gökhan Öğretmenoğlu2, Şansal Gedik3
1Kadirli State Hospital, Clinic of Ophthalmology, Osmaniye, Turkey
Turkish Journal of Ophthalmology
|February 24, 2022
Summary
Spaceflight causes physiological changes, including spaceflight-associated neuro-ocular syndrome. This review explores microgravity and radiation effects on eyes and potential countermeasures.
Area of Science:
- Space Medicine
- Ophthalmology
- Radiation Biology
Background:
- Long-duration spaceflight exposes astronauts to microgravity and space radiation.
- These environmental factors induce significant physiological and pathological changes in human biology.
- Spaceflight-associated neuro-ocular syndrome (SANS) is a key pathological outcome affecting vision.
Purpose of the Study:
- To review existing research on the effects of microgravity and space radiation on ocular structures.
- To analyze the reported results of these spaceflight stressors on the eyes.
- To discuss current and potential treatment strategies for mitigating ocular damage.
Main Methods:
- Comprehensive literature review of studies investigating spaceflight impacts on ocular health.
- Analysis of research focusing on microgravity and space radiation effects.
- Synthesis of findings related to SANS and other visual impairments.
Main Results:
- Microgravity and space radiation demonstrably alter ocular structures and visual function.
- SANS is a recognized condition linked to space travel, encompassing various neuro-ocular changes.
- Data highlights the need for effective countermeasures against these detrimental effects.
Conclusions:
- Understanding the ocular effects of spaceflight is critical for astronaut health.
- Further research into SANS pathophysiology and effective treatments is warranted.
- Developing robust countermeasures is essential for enabling long-duration space missions.
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