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Updated: Oct 2, 2025
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Migraine and Neuroticism: A Scoping Review
Carmen M Galvez-Sánchez1, Casandra I Montoro Aguilar1
1Department of Psychology, University of Jaén, 23071 Jaén, Spain.
Behavioral Sciences (Basel, Switzerland)
|February 24, 2022
Summary
Migraine patients often exhibit higher neuroticism levels, a trait linked to anxiety and emotional disorders. This connection may influence migraine development and severity, suggesting targeted emotional management for better patient care.
Area of Science:
- Neurology
- Psychiatry
- Medical Psychology
Background:
- Headache, particularly migraine, is a leading cause of medical consultations.
- Migraine is a prevalent, disabling primary headache disorder with significant socioeconomic impact.
- Neuroticism, a disposition towards negative emotions, is linked to various mental and physical health conditions, including migraine.
Purpose of the Study:
- To explore the relationship between migraine and neuroticism.
- To enhance understanding of this association for personalized migraine treatment.
- To inform comprehensive approaches for migraine patient care.
Main Methods:
- A scoping review was conducted.
- Searches were performed across PubMed, Scopus, and Web of Science databases.
- 18 relevant articles were selected based on the search terms 'migraine' and 'neuroticism'.
Main Results:
- Neuroticism is highly prevalent in migraine patients.
- Migraine patients with comorbid depression and anxiety display higher neuroticism levels.
- Neuroticism may act as a mediator between childhood maltreatment and migraine, and in the transformation from episodic to chronic migraine.
Conclusions:
- Migraine patients generally exhibit higher neuroticism and negative affect vulnerability than non-migraineurs.
- A clear association exists between neuroticism and migraine, though further research is needed.
- Understanding neuroticism's role can improve migraine management through interventions targeting emotional regulation.
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