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Updated: Oct 2, 2025

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion

Gulshan Walke1, Jana Aupič2, Hadeel Kashoua1

  • 1Department of Chemistry and the Institute of Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Ramat-Gan, Israel.

Biophysical Journal
|February 24, 2022
PubMed
Summary

Human copper transporter Ctr1 (hCtr1) binds multiple copper ions (Cu(I)), triggering structural changes. This reveals how hCtr1 regulates cellular copper uptake and metabolism.

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