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Updated: Oct 2, 2025
Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
Published on: September 14, 2013
High rate of Clostridioides difficile colonization in patients admitted to intensive care: A prospective cohort study
Marcio Fernando Spagnól1, Daniela Signori2, Pedro Henrique Comerlato3
1Universidade Federal do Rio Grande do Sul, Medical Science Post-Graduation Program, Ramiro Barcelos, 2400, Porto Alegre, RS, 90035003, Brazil; Hospital Mãe de Deus, Division of Internal Medicine, R. José de Alencar, 286, Porto Alegre, RS, 90880-481, Brazil.
Abstract:
Here, we evaluated the frequency of C. difficile colonization and its impact on clinical outcomes in patients admitted to intensive care units in Brazil. From ninety-two patients screened 16 (17.3%) were colonized by C. difficile. Colonized patients had higher Simplified Acute Physiology Score III (SAPS III), however there was no association between C. difficile colonization with diarrhea or mortality. The C. difficile strains sequenced belonged to clade 1 and presented high vancomycin-resistant rates.
