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[Oral contraceptives and diabetes].

G Bargero, M Capra Marzani, M Fasano

    Minerva Medica
    |May 7, 1986
    PubMed
    Summary

    This study examines hormonal contraceptives for diabetic women, focusing on how progestins and estrogenic progestins affect carbohydrate/fat metabolism, blood clotting, and blood pressure. It provides guidance on contraceptive use for various diabetic patient groups.

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    Area of Science:

    • Endocrinology
    • Reproductive Health
    • Metabolic Disorders

    Context:

    • Contraceptive use in women with diabetes mellitus requires careful consideration of potential metabolic and cardiovascular risks.
    • Hormonal contraceptives, particularly those containing progestins and estrogenic progestins, can influence glucose and lipid metabolism, hemostasis, and blood pressure.

    Purpose:

    • To review the effects of progestins and estrogenic progestins on carbohydrate and fat metabolism in diabetic females.
    • To discuss the impact of hormonal contraceptives on hemostasis and arterial hypertension in the context of diabetes.
    • To outline indications for contraceptive treatment in insulin-dependent and non-insulin-dependent diabetics, as well as in women at risk of developing diabetes.

    Summary:

    • The relationship between progestins, estrogenic progestins, and metabolic parameters (carbohydrate/fat metabolism, hemostasis, arterial hypertension) in diabetic women using contraceptives is examined.
    • The review provides specific recommendations for initiating contraceptive therapy in diabetic individuals and those with elevated diabetes risk.

    Impact:

    • Informs clinical decision-making regarding the safe and effective use of hormonal contraceptives in women with diabetes.
    • Highlights the importance of individualized risk assessment for diabetic patients considering contraception.
    • Contributes to the understanding of drug interactions between contraceptives and diabetes management.

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