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Updated: Oct 2, 2025

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Ventilation Performance Evaluation of a Negative-Pressurized Isolation Room for Emergency Departments
Fujen Wang1, Indra Permana2, Citra Chaerasari1
1Department of Refrigeration, Air Conditioning and Energy Engineering, National Chin-Yi University of Technology, Taichung 411, Taiwan.
Abstract:
Due to the emergence of COVID-19 becoming a significant pandemic worldwide, hospitals are expected to be capable and flexible in responding to the pandemic situation. Moreover, as frontline healthcare staff, emergency department (ED) staff have a high possibility of exposure risk to infectious airborne. The ED isolation room will possibly and effectively isolate the infected patient, therefore safekeeping frontline healthcare staff and controlling the outbreak. However, there is still limited knowledge available regarding isolation room facilities specifically for the emergency department. In this study, field measurement is conducted in an ED isolation room located in Taiwan. CFD simulation is employed to simulate and investigate the airflow and airborne contaminant distribution. Instead of high air-change rates (ACH) that purposes for dilution, this study proposes the arrangement of exhaust air grilles to improve the contaminant removal. The results reveal that the exhaust air grille placed behind the patient's head is optimized to dilute airborne contaminants.
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Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Mechanical Ventilation I: Indication and Settings
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:

