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Recent Major Transcriptomics and Epitranscriptomics Contributions toward Personalized and Precision Medicine
Ghada Mubarak1, Farah R Zahir2
1Research Institute, Sidra Medicine, Doha, Qatar.
Journal of Personalized Medicine
|February 25, 2022
Summary
Transcriptomics and epitranscriptomics are revolutionizing personalized medicine by improving disease diagnostics and understanding. These "other-omics" fields are crucial for advancing precision medicine beyond genomics.
Area of Science:
- Molecular Biology
- Genetics
- Biomedical Science
Background:
- Genomics initiated the era of precision medicine, with significant contributions to understanding disease.
- Emerging "other-omics" fields, like transcriptomics and epitranscriptomics, are increasingly vital for disease etiology and therapeutic discovery.
Purpose of the Study:
- To review the impact of transcriptomics and epitranscriptomics on personalized and precision medicine.
- To summarize key advancements in cancer, cardiovascular disease, and neurodevelopmental disorders.
Main Methods:
- Review of recent transcriptomic and epitranscriptomic studies.
- Focus on applications in diagnostics and disease pathophysiology.
Main Results:
- Transcriptomics and epitranscriptomics show significant progress in diagnostics for major diseases.
- These fields are crucial for disease pathophysiology research and landscape studies.
Conclusions:
- Transcriptomics and epitranscriptomics are making vital contributions to precision and personalized medicine.
- These "other-omics" fields will significantly enhance the gains achieved by genomics.
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