The ERA Registry Annual Report 2019: summary and age comparisons

Area of Science:

• Nephrology
• Public Health
• Epidemiology

Background:

• The European Renal Association (ERA) Registry collects data on renal replacement therapy (RRT) for end-stage renal disease.
• The 2019 report summarizes data from 34 European and Mediterranean countries, including age-specific comparisons.

Purpose of the Study:

• To report the incidence, prevalence, and treatment modalities of RRT in 2019.
• To analyze kidney transplantation activity and survival probabilities.
• To compare RRT data across different age categories.

Main Methods:

• Utilized individual patient data from 35 registries and aggregated data from 17 registries for 2019.
• Calculated incidence and prevalence of RRT, kidney transplantation rates, and survival probabilities.
• Analyzed data based on age, primary renal disease, treatment modality, and donor type.

Main Results:

• In 2019, RRT incidence was 132 p.m.p. and prevalence was 893 p.m.p. across a population of 680.8 million.
• Haemodialysis (HD) was the predominant initial treatment (84%), with 37% of prevalent patients on HD and 37% living with a kidney transplant.
• Five-year survival probabilities varied significantly by treatment: 42.3% for dialysis, 86.6% for deceased donor grafts, and 94.4% for living donor grafts (2010-14).

Conclusions:

• Significant differences in primary renal disease, treatment, donor type, and survival exist across age groups.
• The ERA Registry provides crucial epidemiological data for end-stage renal disease management in Europe and surrounding regions.
• Age remains a critical factor influencing RRT outcomes and treatment choices.