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Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications.
Yuan Luo1,2,3, Ming Lun Tseng4,5, Sunil Vyas1,3
1Institute of Medical Device and Imaging, National Taiwan University, Taipei, 10051, Taiwan.
Small Methods
|February 25, 2022
Summary
Metasurface optics generate an abrupt autofocusing (AAF) beam for precise optical energy delivery in biomedical applications. This technology shows potential for creating miniature laser surgery instruments.
Area of Science:
- Nanophotonics
- Biomedical Optics
- Optical Engineering
Background:
- Precise control of optical energy delivery is crucial for manipulating biological specimens.
- Metasurface optics offer nanoscale control over light properties, enabling advanced optical manipulation strategies.
Purpose of the Study:
- To demonstrate the generation of an abrupt autofocusing (AAF) beam using a nanophotonic metasurface.
- To investigate the application of AAF beams for selective optical energy delivery in biomedical contexts.
Main Methods:
- Fabrication of a nanophotonic metasurface for AAF beam generation.
- Experimental investigation of fluorescence-guided laser microprofiling on mouse cardiac samples using the AAF beam.
- Photocoagulation of ex vivo swine skin tissue, monitored by optical coherence tomography.
Main Results:
- Successful generation and application of an AAF beam for targeted optical energy delivery.
- Demonstrated selective laser microprofiling of biological tissue.
- Observed effective photocoagulation of tissue, validated by optical coherence tomography.
Conclusions:
- Metasurface-generated AAF beams provide a powerful tool for precise optical energy manipulation in biological samples.
- The technology holds significant promise for the development of miniaturized laser surgery instruments for diverse biomedical applications.
