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Continuous Lactate Monitoring System Based on Percutaneous Microneedle Array
Ming-Nan Chien1,2, Shih-Hao Fan1, Chi-Huang Huang3
1Department of Mechanical Engineering, National Taipei University of Technology, No. 1, Sec. 3, Zhongxiao E. Rd., Da'an Dist., Taipei City 10608, Taiwan.
Sensors (Basel, Switzerland)
|February 26, 2022
Summary
A new continuous lactate monitoring system (CLMS) using microneedles offers a low-cost, non-invasive method for tracking lactate levels. This system can assess exercise performance and training intensity, aiding athletes and medical professionals.
Area of Science:
- Biomedical Engineering
- Sports Science
- Medical Diagnostics
Background:
- Lactate accumulation impacts athletic performance and is a key sepsis indicator.
- Current blood sampling methods for lactate measurement lack continuous monitoring capabilities.
Purpose of the Study:
- To develop a low-cost continuous lactate monitoring system (CLMS) using a microneedle array.
- To evaluate the CLMS for assessing exercise performance and training intensity.
Main Methods:
- A microneedle array sensor with gold, polyaniline, lactate enzyme, Nafion, and poly HEMA was fabricated.
- The sensor was integrated into a CLMS connected to a smartphone app and cloud.
- The system was tested on 40 subjects during graded exercise tests on indoor bicycles.
Main Results:
- The CLMS successfully acquired and analyzed lactate response data during exercise.
- The system demonstrated feasibility in assessing exercise performance and training intensity.
Conclusions:
- The developed CLMS provides a viable, low-cost solution for continuous lactate monitoring.
- This technology has potential applications in sports science and medical diagnostics, particularly for sepsis prognosis.
