Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A randomized comparison of classical mode of administration of amphotericin B with its newer modes of administration in kala-azar.

The Journal of the Association of Physicians of India·2001
Same author

Relaxin decreases renal interstitial fibrosis and slows progression of renal disease.

Kidney international·2001
Same author

A polystyrene based membrane electrode for cadmium(II) ions.

Fresenius' journal of analytical chemistry·2001
Same author

The circadian pattern of ischaemic heart disease events in Indian population.

The Journal of the Association of Physicians of India·2001
Same author

Amberlite XAD-7 impregnated with Xylenol Orange: a chelating collector for preconcentration of Cd(II), Co(II), Cu(II), Ni(II), Zn(II) and Fe(III) ions prior to their determination by flame AAS.

Fresenius' journal of analytical chemistry·2001
Same author

Evolution of otogenic brain abscess and management protocol.

Indian pediatrics·2001

Related Experiment Video

Updated: Oct 2, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.9K

Single-Fraction Stereotactic Ablative Body Radiotherapy to the Lung - The Knockout Punch.

M C Tjong1, A V Louie1, A K Singh2

  • 1Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|February 28, 2022
PubMed
Summary

Single-fraction stereotactic ablative body radiotherapy (SABR) shows promise for lung cancer and metastases, offering an alternative to multi-fraction SABR. This review compares efficacy and safety, considering radiobiological and technical factors.

Keywords:
AblativeNSCLClungmetastasisradiotherapystereotactic

More Related Videos

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.4K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.3K

Related Experiment Videos

Last Updated: Oct 2, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.9K
Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.4K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.3K

Area of Science:

  • Radiation Oncology
  • Thoracic Oncology
  • Medical Physics

Background:

  • Stereotactic ablative body radiotherapy (SABR) is increasingly used for lung cancers and metastases.
  • Multi-fraction SABR regimens are widely adopted, but single-fraction approaches are emerging.
  • Evidence comparing single-fraction and multi-fraction SABR for lung tumors requires synthesis.

Purpose of the Study:

  • To summarize current evidence on the efficacy and safety of single-fraction SABR for primary lung cancers and lung metastases.
  • To compare single-fraction SABR with multi-fraction SABR regimens.
  • To discuss radiobiological, technical, and organ-at-risk considerations for single-fraction SABR in the lung.

Main Methods:

  • Literature search of the Medline database via PubMed.
  • Keywords included 'stereotactic', 'sabr', 'sbrt', 'radiotherapy', 'lung', 'cancer', 'metastases'.
  • Specific searches for 'single-fraction' studies and randomized controlled trials comparing different fractionations were performed.

Main Results:

  • Evidence on efficacy and safety of single-fraction SABR for lung tumors is summarized.
  • Comparisons are drawn between single-fraction and multi-fraction SABR regimens.
  • Radiobiological, technical, and organ-at-risk factors relevant to single-fraction lung SABR are discussed.

Conclusions:

  • Single-fraction SABR presents a viable option for treating lung cancers and metastases.
  • Further research and comparative studies are needed to fully establish its role.
  • Understanding the nuances of single-fraction SABR is crucial for optimizing treatment outcomes.