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Related Concept Videos

Sleep-Wake Cycles01:24

Sleep-Wake Cycles

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Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
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Substance Use Disorders Affecting Sleep01:24

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
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Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

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Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
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Insomnia01:27

Insomnia

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Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
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REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

456
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
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Narcolepsy01:07

Narcolepsy

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Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
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Updated: Oct 2, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
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Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

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Cancer-Related Sleep Wake Disturbances.

Ellyn E Matthews1, Shu-Yi Wang1

  • 1Professor, Rueckert-Hartman College for Health Professions, Regis University, Denver, Colorado.

Seminars in Oncology Nursing
|February 28, 2022
PubMed
Summary
This summary is machine-generated.

Sleep-wake disturbance (SWD) is common in cancer patients, impacting recovery. Addressing SWD with interventions like cognitive behavioral therapy for insomnia (CBTI) is crucial for better outcomes.

Keywords:
CancerCognitive behavioral therapy (CBT)Difficulty falling asleepDifficulty maintaining sleepInsomniaNonrestorative sleepSleep-wake disturbance

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Area of Science:

  • Oncology
  • Sleep Medicine
  • Psychosocial Oncology

Background:

  • Sleep-wake disturbance (SWD) is a prevalent issue in adult cancer patients.
  • SWD significantly impacts physical and psychological recovery from cancer.
  • Contributing factors include cancer-related physical symptoms and psychological distress like anxiety and fatigue.

Purpose of the Study:

  • To review evidence on SWD in adults with cancer.
  • To update knowledge on prevalence, impact, causes, risk factors, assessment, and treatments.
  • To explore emerging science and technology in SWD management.

Main Methods:

  • Synthesis of review articles.
  • Analysis of sources from electronic databases.

Main Results:

  • SWD is a prevalent and debilitating problem for cancer patients.
  • Untreated SWD negatively affects recovery.
  • Multiple factors, including physical and psychological symptoms, contribute to SWD.

Conclusions:

  • Prioritizing sleep in cancer care is essential.
  • Effective treatments include psychosocial interventions and behavioral therapies like cognitive behavioral therapy for insomnia (CBTI).
  • Exercise and mindfulness-based stress reduction show promise in diminishing SWD.