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Understanding Pacemaker-Induced Cardiomyopathy Incidence and Predictors in Patients with Right Ventricular Pacing: A
Sidhi Laksono1,2, Budhi Setianto3, Mohammad Iqbal4
1Department of Cardiology and Vascular Medicine, RS Pusat Pertamina, South Jakarta, Indonesia.
Summary
Pacemaker-induced cardiomyopathy (PICM) affects 10.7-13.7% of patients with right ventricular pacing. Key predictors include preimplantation ejection fraction and pacing burden, highlighting risks associated with RV pacing.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Research
Background:
- Right ventricular (RV) pacing is a common treatment for bradyarrhythmias.
- Pacemaker-induced cardiomyopathy (PICM) is a potential complication of long-term RV pacing.
- Understanding PICM incidence and predictors is crucial for patient management.
Purpose of the Study:
- To determine the incidence of PICM in patients undergoing RV pacing.
- To identify predictors associated with the development of PICM.
Main Methods:
- Systematic literature search of PubMed for relevant studies published in English.
- Inclusion criteria focused on pacemaker-induced cardiomyopathy, right ventricular pacing, and human patients.
- Analysis of four selected studies involving 1,365 patients.
Main Results:
- The overall incidence of PICM ranged from 10.7% to 13.7% across the included studies.
- Preimplantation left ventricular ejection fraction (LVEF) was identified as a predictor in one study.
- Right ventricular pacing burden (≥20%, >40%, or 60%) and interventricular dyssynchrony were also reported as predictors.
Conclusions:
- PICM occurs in a significant percentage of patients with RV pacing.
- Preimplantation LVEF, RV pacing burden, and interventricular dyssynchrony are key predictors for PICM development.
- These findings emphasize the need for careful patient selection and monitoring in RV pacing.
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