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P2X7 Receptor Triggers Lysosomal Leakage Through Calcium Mobilization in a Mechanism Dependent on Pannexin-1

Stephanie Alexia Cristina Silva Santos1, Pedro Muanis Persechini2, Bianca Monteiro Henriques-Santos3

  • 1Laboratory of Molecular Biology and Biochemistry of Proteins, Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Frontiers in Immunology
|February 28, 2022
PubMed

Keywords:
P2 receptorcathepsinsextracellular ATPlysosomal permeabilizationlysosomes

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