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Updated: Oct 2, 2025

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery
Published on: April 10, 2014
Mediastinal Rhabdomyosarcoma Feeding Off the Left Anterior Descending Artery
Milena Guenther1, Markus Richter1, Torsten Doenst1
1Department of Cardiothoracic Surgery, Jena University Hospital, Jena, Thüringen, Germany.
Abstract:
We report the rare case of a 51-year-old patient with a 15 cm mediastinal rhabdomyosarcoma with blood supply from the left anterior descending artery presenting as a large mass including the pericardium with extensive contact to the epicardium compressing heart and left lung. The tumor was successfully removed through median sternotomy, blunt dissection from the heart and the left lung, resection of the infiltrated pericardium, and ligation of the tumor-feeding vessels using off-pump stabilizers. Histopathological examination revealed a spindle cell rhabdomyosarcoma with R0 resection. The postoperative course was uneventful, and patient is feeling well at 3-month follow-up.
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