Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

570
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
570
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.2K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.2K
Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

330
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
330

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Scout-based Multi-Echo NAvigator (SMENA) for high temporal resolution motion and B <sub>0</sub> estimation and correction: applications to multi-echo GRE and EPTI.

bioRxiv : the preprint server for biology·2026
Same author

Mapping subarachnoid cerebrospinal fluid circulation in the human brain.

bioRxiv : the preprint server for biology·2026
Same author

Neural activity drives directional subarachnoid cerebrospinal fluid flow in the human brain.

bioRxiv : the preprint server for biology·2026
Same author

Multiphasic myelination and dendritic growth modulate qMRI signals in human visual cortex.

bioRxiv : the preprint server for biology·2026
Same author

Water/Fat Separated Echo Planar Time-Resolved Imaging (WFS-EPTI) for Distortion-Free Multi-Contrast MRI.

Magnetic resonance in medicine·2026
Same author

Semi-supervision for clinical contrast-weighted image synthesis from magnetic resonance fingerprinting.

Magma (New York, N.Y.)·2026

Related Experiment Video

Updated: Oct 2, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.4K

SNR-efficient distortion-free diffusion relaxometry imaging using accelerated echo-train shifted echo-planar

Zijing Dong1,2, Fuyixue Wang1,3, Lawrence Wald1,3

  • 1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

Magnetic Resonance in Medicine
|February 28, 2022
PubMed
Summary

A new accelerated echo-train shifted echo-planar time-resolved imaging (ACE-EPTI) technique provides high-quality, distortion-free diffusion MRI and diffusion-relaxometry. This efficient method achieves submillimeter resolution with improved signal-to-noise ratio compared to conventional techniques.

Keywords:
EPTIdiffusion imagingdiffusion relaxometrydistortion correctionhigh resolutionhigh SNR

More Related Videos

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.7K
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

22.7K

Related Experiment Videos

Last Updated: Oct 2, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.4K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.7K
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

22.7K

Area of Science:

  • Magnetic Resonance Imaging
  • Diffusion MRI
  • Quantitative MRI

Background:

  • Diffusion MRI is crucial for neuroimaging but often suffers from distortions and low signal-to-noise ratio (SNR).
  • Existing techniques struggle to balance resolution, speed, and image quality, limiting diffusion-relaxometry applications.

Purpose of the Study:

  • To develop an efficient acquisition technique for distortion-free diffusion MRI and diffusion-relaxometry.
  • To achieve high-SNR, submillimeter resolution, and artifact-free imaging using accelerated acquisition.

Main Methods:

  • Introduced accelerated echo-train shifted echo-planar time-resolved imaging (ACE-EPTI) with variable density spatiotemporal encoding and self-navigators.
  • Employed echo-train shifting for minimal TE and optimized readout length for SNR efficiency.
  • Utilized a subspace image reconstruction framework for phase correction and artifact removal.

Main Results:

  • ACE-EPTI achieved submillimeter in-plane resolution with a 3-shot acquisition.
  • Demonstrated 27%-36% SNR efficiency improvement over single-shot EPI.
  • ACE-EPTI images showed no noticeable susceptibility or eddy-current distortions, unlike conventional EPI.

Conclusions:

  • ACE-EPTI is an efficient technique for high-resolution diffusion imaging and diffusion-relaxometry.
  • Provides high SNR, distortion-free, and time-resolved multi-echo images.
  • Enables advanced quantitative MRI analyses through fast, high-quality data acquisition.