Semi-supervision for clinical contrast-weighted image synthesis from magnetic resonance fingerprinting

To facilitate ease of data compilation across diverse populations for training models to synthesize clinical contrast-weighted images from magnetic resonance fingerprinting.

We leverage a semi-supervised training framework using highly accelerated acquisitions of the target contrasts used as ground truths. We utilize complementary randomized data sampling masks across training subjects and contrasts for homogeneous learning in k-space, together with multi-task learning.

Our experiments indicate that the proposed method achieves high-quality synthesis with networks trained on retrospectively and prospectively undersampled data of the contrast-weighted images, enabling undersampling up to 12-16 $\times$ .

The proposed method enables semi-supervised learning for synthesis from MRF with an end-to-end, ultra-fast training data acquisition protocol that is easier to obtain across a large population in clinical settings.