Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Capecitabine Dosage as an Independent Prognostic Factor for the Development of Hand-Foot Syndrome: A Competing Risk Analysis.

Drug, healthcare and patient safety·2026
Same author

Efficacy of Omitting H2 Antagonists versus Famotidine in Taxane Hypersensitivity Reactions Prophylaxis: A Randomized, Prospective, Open-Label, Controlled Trial.

Asian Pacific journal of cancer prevention : APJCP·2024
Same author

Predictive factors for the development of capecitabine-induced hand-foot syndrome: a retrospective observational cohort study.

Annals of medicine and surgery (2012)·2024
Same author

Efficacy of Short Hydration for Intermediate to High-Dose Cisplatin-Based Chemotherapy for Outpatients: SHORTCIS Trial.

Asian Pacific journal of cancer prevention : APJCP·2022
Same author

Prognostic Value of the Pre-Treatment Prognostic Nutritional Index for Patients with Unresectable Locally-Advanced and Advanced Stage Upper Gastrointestinal Tract Cancer.

International journal of general medicine·2022
Same author

Efficacy of Premedication Protocol without Ranitidine for Taxane Regimen: A Multicenter Non-Randomized Historical Controlled Study.

Asian Pacific journal of cancer prevention : APJCP·2022

Related Experiment Video

Updated: Oct 2, 2025

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
07:00

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

9.0K

Prognostic Scoring System Development for Malignant Spinal Cord Compression.

Chaichana Chantharakhit1, Nantapa Sujaritvanichpong1

  • 1Division of Medical Oncology, Department of Internal Medicine, Buddhasothorn Hospital, Chachoengsao, Thailand.

Asian Pacific Journal of Cancer Prevention : APJCP
|February 28, 2022
PubMed
Summary
This summary is machine-generated.

A new prognostic scoring system, the Buddhasothorn Hospital Malignant Spinal Cord Compression (BSH-MSCC) score, accurately predicts survival in patients with malignant spinal cord compression. This tool aids in treatment decisions for improved patient outcomes.

Keywords:
Malignant spinal cord compressionprognostic scoretreatment modality

More Related Videos

A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat
05:51

A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat

Published on: June 29, 2021

1.5K
Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
08:08

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy

Published on: October 16, 2013

10.8K

Related Experiment Videos

Last Updated: Oct 2, 2025

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
07:00

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

9.0K
A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat
05:51

A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat

Published on: June 29, 2021

1.5K
Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
08:08

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy

Published on: October 16, 2013

10.8K

Area of Science:

  • Oncology
  • Spinal Surgery
  • Biostatistics

Background:

  • Malignant spinal cord compression (MSCC) poses significant survival challenges.
  • Existing prognostic scoring systems for MSCC often lack sufficient accuracy.
  • Advanced cancer therapies necessitate updated survival prediction models.

Purpose of the Study:

  • To develop a novel, highly accurate prognostic scoring system for malignant spinal cord compression (MSCC).
  • To improve survival prediction in MSCC patients, aiding clinical decision-making.

Main Methods:

  • Analysis of clinical data from 89 MSCC patients (2018-2020).
  • Univariate and multivariate Cox's regression analysis to identify prognostic factors.
  • Development and internal validation (bootstrapping) of the Buddhasothorn Hospital Malignant Spinal Cord Compression (BSH-MSCC) score.

Main Results:

  • Nine prognostic factors identified: Neutrophil-to-Lymphocyte ratio >3.6, specific cancer types (breast, lung, other), male sex, complete paralysis, spinal metastases in three levels, hypercalcemia, and lack of systemic treatment.
  • The BSH-MSCC score (0-52 points) demonstrated strong predictive accuracy (AUC=0.77).
  • The score effectively predicted short-term survival (AUC=0.93), with a cut-off >18 showing high sensitivity (81.5%) and specificity (85.7%).

Conclusions:

  • The BSH-MSCC score offers a simplified and highly accurate method for predicting survival in MSCC patients.
  • This new tool enhances clinical decision-making within a multidisciplinary approach.
  • The BSH-MSCC score represents a valuable advancement in managing malignant spinal cord compression.